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02/01/2009
Inside your lungs are millions of very small blood vessels called capillaries...
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PPH Cure Foundation
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Recognition to Outstanding Researchers

At the August 1996 meeting of the Untied Patients Association for Pulmonary Hypertension (UPAPH), the PPH Cure Foundation awarded its first Scientific Progress Award to Dr. Robyn Barst, M.D., Director of the Children's Pulmonary Hypertension Center at the Columbia Presbyterian Hospital in New York. Dr. Barst donated her cash award of $18,000 to the laboratory of her collaborator, Dr. Jane Morse, which has made outstanding progress in the genetics of particular autoimmune dysfunctions affecting patients with PPH. The work of Drs. Barst and Morse may very well lead to immunosuppressive therapeutic interventions in subsets of patients with primary pulmonary hypertension.

Dr. Barst's Children's Pulmonary Hypertension Center is the only pediatric facility of this sort in the world, and her clinical practice involves the world's largest caseload of pediatric PPH patients. Dr. Barst's landmark 1996 article in the New England Journal of Medicine, "A Comparison of Continuous Intravenous Epoprostenol (Prostacyclin) with Conventional Therapy in Primary Pulmonary Hypertension" reported on the scientific results of the clinical trial that led to FDA approval of Glaxo-Wellcome's Flolan as the first therapeutic agent approved for PPH.

The Foundation has made a proposal to the American Thoracic Society for a Foundation-funded permanent award to two researchers each year at the Society's annual meeting. The purpose of the Foundation's recognition awards is to compensate for the fact that because PPH is a rare disease, researchers working on it do not receive as much support as their colleagues working on more prevalent diseases. The Foundation hopes that its awards program will bring PPH research to the attention of more investigators, and will thereby attract more scientists to the field and enhance the momentum toward a cure. The Foundation has budgeted $36,000 for its Scientific Progress Awards in 1997.